Welcome to Metabolic Biochemistry at the Biology Department at the University of California, San Diego. This course is taught by Dr. Lukas Buehler. The goal is to understand energy producing pathways (glycolysis, citric acid cycle, oxidative phosphorylation, photosynthesis, and fatty acid oxidation) and biosynthetic pathways (gluconeogenesis, glycogen synthesis, fatty acid synthesis, and amino acid and nucleic acid metabolism) including the metabolism of signaling molecules like neurotransmitters and steroid hormones. The course pays particular attention to human physiology, and the structural organization of pathways is discussed in terms of cellular location and compartmentalization, as well as coordination of pathways among different organs (metabolic integration). The importance of biological membranes for metabolic integration and regulation is addressed through discussions of transport systems for small metabolites as well as the central role of membrane biogenetic pathways in human lipid metabolism.


BIBC 102 Summer 2008

MTWTh 12:30pm - 1:50pm Solis 107

  Contact

Instructor

Dr. Lukas Buehler
TAs Farnaz Ehya
  Polly Huang
  Ching Wang
  Jiwon Youm
  Gary Liu
Updates

I will have office hours this week on Thursday 8/14 from 11am-1pm.

Finale exam: exam key (Note for key: #2 should say ACP or acyl carrier protein, not APC)
Exams are now available outside 3230 Bonner Hall. If you did not sign the waiver, please pick up your exam from Crystal Warning in room 3234 Bonner Hall with your ID.

Grade* Final Class total
A 110-140 260-340
B 94-109 225-259
C 78-93 190-224
D 62-77 155-189
* How to read this table and calculate + and - grades: pluses and minuses are the lower and upper 10p range of the grade range shown above; e.g. an A minus is from 260 to 269 points, a C+ from 215 to 224 points.

Study guide for final exam; sample final exam
Final exam includes: fatty acid metabolism, glycerolipid and sterol metabolism, nitrogen and amino acid metabolism, and nucleic acid metaolism

Results for midterm 2:
Exam Key; Grade range: A 80-100; B 68-79; C 56-67; D 44-53 points; Cumulative grade range: A 160-200; B 135-159; C 110-134; D 85-104 points

Regrade requests for 2nd midterm must be made no later than Tue 7/29. Please contact the TAs as follow: [1&2: Gary], [3&4: Polly], [5&6: Farnaz], [7&8: Ching], [9&10: Jiwon]

Study guide for midterm 2, sample exam
Review session: Tue 7/22 from 7-9pm, location CSB 001
Review material

Dr. Buehler's Office Bonner Hall 3230 (not 3220)

Syllabus

Course Calendar and policy information
The lectures of this course are available as podcast.
Download PDF file of course syllabus

Grading

Midterm 1     30%; Results: Exam key (correction: answer to question 7 includes AMP, should be ATP); Grades: 78-100p A; 66-77p B; 54-65p C; 42-53p D
Regrading: please contact the appropriate TA for each question : 1&2: Jiwon, 3&4: Polly, 5&6: Ching, 7&8: Farnaz, 9&10: Gary; requests have to be sumbitted no later than Th 7/17

Midterm 2     30%
Final exam   40%
   
   

Internet KEGG pathway database (Kyoto Encyclopedia of Genes and Genomes)
 

Text books Metabolic Biochemistry
(custom reader)
by Lukas K. Buehler
Publisher: J.Wiley & Sons

Fundamentals of Biochemistry, 3rd ed.
by Voet, Voet and Pratt
J.Wiley & Sons, 2008

Available at Biomed Library Reserves


Please send any questions or comments regarding this class to Lukas Buehler
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TA sections, office hours and handouts Course calendar and links to lecture slides