Syllabus
BIBC 100 Summer 2001
Lecture: M/T/W/Th 5:00-6:20PM
Center Hall 115
Instructor: Lukas Buehler, Bonner Hall 2402, Office Hours Thursday
3-4 PM
Contact: Tel 822-1311, lbuehler@ucsd.edu
Secretarial support: Jacqueline Richardson, York Hall 3080A, M-F 9
AM - 5 PM
| Week |
Date |
Topic |
Cox, Lehninger 3rd edition *
|
I. Building Principles of Macromolecules
| 1 |
M July 2 |
Aqueous solutions, Hydrophobic effect |
1-4
|
|
Tu July 3 |
Protein structure I: Amino acids |
5
|
|
W July 4 |
Holiday |
-
|
| |
Th July 5 |
Protein Structure II: a
-helix; b -sheet, turns |
6
|
| 2 |
M July 9 |
DNA and RNA structure |
10
|
| |
Tu July 10 |
Polysaccharides |
9
|
| |
W July 11 |
Lipids and membrane structure |
11,12
|
|
Th July 12 |
Structure determination techniques |
6
|
| 3 |
M July 16 |
Midterm (during class; 40% of grade) |
Exam
|
II. Structure - Function Relationship of
Proteins
| |
Tu July 17 |
Enzyme kinetics: Serine proteases |
8
|
| |
W July 18 |
Ligand binding: Hemoglobin |
7
|
|
Th July 19 |
Metalloproteins, Pumps, Channels |
12,13
|
| 4 |
M July 23 |
Acetylcholine receptor; potassium channel |
13
|
| |
Tu July 24 |
Electron transport, Bacterial photosynthesis |
19
|
|
W July 25 |
Protein motion; Protein folding; Self-assembly |
6
|
III. The Structural Basis of Cellular Mechanisms
|
Th July 26 |
Protein-DNA interaction; transcription factors |
24,28
|
| 5 |
M July 30 |
Cytoskeleton: molecular motors |
2
|
| |
Tu July 31 |
Glycoproteins, Lectins |
9,27
|
| |
W August 1 |
Antibodies; cell surface receptors; cadherins |
7,13
|
|
Th August 2 |
HIV host cell recognition |
12
|
| |
F Friday 3 |
Final Exam (9-11:50 AM, Center 119; 60%) |
Exam
|
* Chapters indicated cover
much more material than discussed during class. Please use the Class Reader
as guide for topics covered. Use the text book selectively by looking up
table of contents and keyword index. Figures from the text book will be
used during lecture. This figures also indicated which sections in each
chapter to focus on.
|