Introduction to Protein Structure. 
C. Branden and J.Tooze, 2nd Edition.  Garland Publishing Co., NY 1999.

Kinemage Supplement to Branden and Tooze
J.S. Richardson and D.C. Richardson   Garland Publishing Co., NY

Class Reader:  Structural Biochemistry 2e. 
L. Buehler. Wiley, 2002

Course Requirements:	GRADE
Midterm: Thursday, February 6, during class	40%
Final:   Thursday, March 20, 8:00 – 11:00 A.M.	60%

(Note: final exam is cummulative; exams include assigned papers)

GRADING INFORMATION:  Plus and minus grading will not be used

MIDTERM:  Grade Revisions:
Submit request to TA no later than February 14, 2003
No grade changes after February 21, 2003
NO EXCEPTIONS

FINAL:  Grade Revisions:
Submit request to Professor or TA no later than March 27, 2003
No grade changes after April 1, 2003
NO EXCEPTIONS

#1 de Vos, A.M., Ultsch, M., Kossiakoff, A.A. (1992).
Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science 255:360-312

#2 Deisenhofer, J., Epp, O., Miki, K., Huber, R., Michel, H. (1985).
Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3A resolution.  Nature 318:618-624

#3 Unwin, N. (1995).
 Acetylcholine receptor channel image in the open state.  Nature 373:37-43

#4 Milburn, M.V., Tong, L., de Vos, A.M., Brunger, A., Yamaizumi, Z., Nishimura, S., Kim, S.H. (1990).
Molecular switch for signal transduction: structural difference between active and inactive forms of proto-oncogenic ras proteins.  Science 247:939-945.

#5 Navia, M.A., Fitzgerald, P.M.D., McKeever, B.M., Leu, C.T., Heimbach, J.C., Herber, W.K., Sigal, I.S., Darke, P.L., Springer, J.P. (1989). Three-dimensional structure of aspartylprotease from human immunodeficiency virus HIV-1.  Nature 337:615-620

1. All writing instruments must contain non-erasable ink.  If students choose not to write in pen, they forfeit the opportunity for a future regrade.

2. All books and handbags should be placed at the front or back section of the auditorium for the duration of the exam.

3. Students should sit in alternating seats whenever possible.

4. When time is called, anyone who is still writing will automatically receive a zero for that page.  THIS WILL BE STRICTLY ENFORCED.  Remain in your seat and hand your exam down the aisle.
 

UCSD policy on integrity of scholarship (UCSD catalog 00-01, pages 72-74) and Rules of academic dishonesty will be strictly enforced.