Summer 2004
Syllabus * Sections * Office Hours * KEGG
Welcome
to Metabolic Biochemistry at the Biology Department at the University of
California, San Diego for Summer 2004. This course is taught by Dr. Lukas
Buehler. The goal is to understand energy producing pathways (glycolysis,
citric acid cycle, oxidative phosphorylation, photosynthesis, and fatty
acid oxidation) and biosynthetic pathways (gluconeogenesis, glycogen synthesis,
fatty acid synthesis, and amino acid and nucleic acid metabolism) including
the metabolism of signaling molecules like neurotransmitters and steroid
hormones. The course puts an emphasis on human metabolism and pathways
are discussed in terms of cellular location and compartmentalization,
as well as coordination of pathways among different organs (metabolic integration).
The importance of biological membranes for metabolic integration and regulation
is addressed through discussions of transport systems for small metabolites
as well as the central role of membrane biogenetic pathways in human lipid
metabolism. Updates
and exam keys
Final info : Exam Key
Exams and grades will be available Tue 8/3
Pickup Location: York Hall 3080
(if waiver not signed, please see Shiwan Tribbett in 3080E)
Regrades: in writing only; please leave request in Buehler mailbox
at York 3080C
Stats: Final Exam 280±75; Class total 700±150
Grades (cutoffs):
A+ 960; A 890; A- 850
B+ 810; B 740; B- 700
C+ 660; B 590; C- 550
D 400
Jonathan new handouts on phospholipid synthesis, cholesterol, desaturases and oxygenases, amino acids and SAM/THF
Midterm 1 Key
Class average 206; distribution ±50
(est. grade range A>250; B>200; C>150)
Regrading: ends Monday 7/19; for requests, please contact the following
TAs: Irena graded Q 1,2,&3; Jonathan graded Q 4,5,&6;Jamal and
Tiffany graded Q 7,8,&9
Midterm 2 key (exams returned M during class)
Please note that the last day of class and the final exam are Friday 7/30.
AS Lecture Note taker for this class is Lindsay Fox
Use the study guide for midterms and
final exam
Sample exams: midterm
/ final
Textbooks:
1. Class Reader, available at University Bookstore
2. Principles of Biochemistry Lehninger, Nelson, Cox, 3rd, 2000
Course requirements
and Grade: 1. Midterm: 30%
2. Midterm: 30%
3. Final Exam: 40% (last day of class )
Teaching
Assistants
| Jonathan Dang | jmdang@ucsd.edu |
| Jamal Nabhani | jnabhani@ucsd.edu |
| Irena Stijacic | istijaci@ucsd.edu |
| Tiffany Lau | tiffanylauca@hotmail.com |
Internet
Special attention will be given to pathway comparison
among different species. This aspect of the course will be based on public
databases and specifically the metabolic pathway database at the Kyoto
Encyclopedia of Genes and Genomes (KEGG)
at the Japanese Genomenet WWW Server.
Syllabus | Sections | Office Hours | KEGG
Please send any questions or comments regarding this class to Lukas Buehler