Metabolic
Biochemistry 
General Information - Winter 2006
Instructor: Immo E. Scheffler
Office: 3202
Bonner Hall
Office Hours: 11 - ~ noon, every day; 2 - 4 PM with appointments by e-mail
Telephone Contact: 534-2741 : E-mail:
ischeffler@ucsd.edu
Secretary: Dawna Cogan, 3234 BH
Teaching Assistants:
Deanne Alpert dalpert@ucsd.edu #1,
Edward Chen e8chen@ucsd.edu #1 , #2, #3, #4, #5, #6, #7,
Melody Daroogar mdarooga@ucsd.edu #1, #2 , #3 , #4 , #5 , #6, #7, #8,
Rick Mathewson rmathews@ucsd.edu
Rachel Ochoa rlochoa_85@earthlink.net RO website
Erin Scott emscott@ucsd.edu
Suzanne Wolff swolff@ucsd.edu
Lectures: MW 7:30 AM - 8:50 AM CENTR 101
Sections:
A01 M 1-1:50 CENTR 218
A02 M 2-2:50 CENTR 218
A03 M 3-3:50 CENTR 218
A04 M 4-4:50 CENTR 218A05 Tu 8-8:50 CENTR 203
A06 Tu 9-9:50 CENTR 203A07 W 12-12:50 HSS 2321
A08 F 8-8:50 CENTR 203
A09 F 3-3:50 CENTR 203
A10 F 4-4:50 CNETR 203
room capacity is limited; sign up for a section to be sure to get in
Course Outline for Winter 2006
TEXTBOOKS
PRINCIPLES OF BIOCHEMISTRY by Lehninger,
Nelson and Cox; Fourth Edition (2004) with CD ROM
(this book will also have the problems to be covered in sections)
The Absolute, Ultimate Guide to Lehninger
Principles of Biochemistry (Fourth Edition) is a Study Guide
and Solutions Manual written by M. Osgood and K. Ocorr. It contains a step-by-step
guide to the major priniciples and a series of questions and answers for
self-study. These questions are in addition to the questions at the end
of each chapter in the textbook itself. I recommend the study guide strongly.
There is also a Lecture Notebook,
described as an "indispensable classroom companion" allowing you
to take "meaningful notes and listen attentively". I frankly believe that
you should listen attentively and take your own notes in class, - then
go to the text or come to me if they are not clear.
In the lectures there will be Power Point presentations, and all the diagrams shown in classs will be from the textbook. Thus, if you have the book, you will not have to copy from the screen.
If you have an older edition of Lehninger (3rd) and wish to save $$$, it is perfectly useful. Most if not all the material covered in this course can be found in the older book, but you should be aware that in the new book the Chapter Numbers and the Figure Numbers are somewhat different. For example, I have always combined the discussion of glycogen breakdown and glycogen synthesis. In the previous edition these topics were in Chapters 15 and 20; now they have been combined in Chapters 14 and 15.
The assignment of problems for the Sections will be from the new book. Chapter Numbers and Question Numbers may have changed.
The following textbooks are also very good books to learn the basic material;
they do not have the problems to be covered in sections.
BIOCHEMISTRY by Mathews, Van Holde and Ahern; Third
Edition (2000)
BIOCHEMISTRY by Voet and Voet is an excellent,
but very detailed text; a third edition has just been published
BIOCHEMISTRY by Stryer will also serve well (a new edition has been published recently)
SECTIONS
Sign-up sheets for the Sections with the times and names of the TA will be posted outside of my office during the first week. Sections will be filled on a first come basis. The capacity of each Section is limited by the room size.
Midterm Exam (2 hours, 40% of grade);
DATE AND TIME: Thursday, Feb. 16 7 - 8:50 PM PETER 108
Final Exam (3 hours ,60% of grade);
DATE AND TIME: Monday, March 20, 8 - 11 AM
PLACE: CENTR 101( possibility of an alternate room ?? )
W I02 (sample)
Final Exam WI 04 (sample)
Both exams will be based on the Lectures and on the Problem Set
NO CALCULATORS NEEDED AND NONE WILL BE ALLOWED INTO
THE EXAM
All exams are to be written in ink
REGRADES: Addition errors will will corrected at once; other complaints/objections must be made in writing and turned in with the exam; the entire exam may be reviewed.
Many links to the Internet are given on the CD ROM that comes with the LNC textbook; specific recommendations will be made in class.
Images of Biological Macromolecules (from L. Buehler's Web site for Structural Biology)
Kyoto Encyclopedia of Genes and Genomes
Online Mendelian Inheritance in Man (OMIM)
the best source for information on human genetic diseases (pathology, biochemistry,
genetics, etc)