Relevant Publications

[Forbes Home]


Forbes, D., Kirschner, M.W., Newport, J. (1983). Spontaneous formation of nucleus-like structures
around bacteriophage DNA microinjuected into Xenopus eggs. Cell , 34, 13-23. PDF

Forbes, D. J., Kirschner, M.W., Caput, D., Dahlberg, J.E., and Lund, E. (1984). Differential expression
of multiple U1 small nuclear RNAs in oocytes and embryos of Xenopus laevis. Cell, 38, 681-689. PDF

Newmeyer, D.D., Finlay, D.R., and Forbes, D.J. (1986). In vitro transport of a fluorescent nuclear protein and exclusion of non-nuclear proteins. J. Cell Biology, 103, 2091-2102. PDF

Finlay, D.R., Newmeyer, D.D., Price, T.M., and Forbes, D.J. (1987). Inhibition of in vitro nuclear
transport by a lectin which binds to nuclear pores. Journal Cell Biology, 104, 189-200. PDF

Newmeyer, D.D. and Forbes, D.J. (1988). Nuclear import can be separated into distinct steps
in vitro: Nuclear pore binding and translocation. Cell, 52, 641-653. PDF

Finlay, D.R. and Forbes, D.J. (1990). Reconstitution of biochemically altered nuclear pores: Transport
can be eliminated and restored. Cell, 60, 17-29. PDF

Newmeyer, D. and Forbes, D. (1990). An N-ethylmaleimide-sensitive cytosolic factor necessary for
nuclear protein import: Requirement in signal-mediated binding to the nuclear pore.
J. Cell Biology, 110, 547-557. PDF

Finlay, D.R., Meier, E., Bradley, P.J., Horecka, J., and Forbes, D.J. (1991). A complex of nuclear pore
proteins required for pore function. Journal Cell Biology, 114, 169-183. PDF

Forbes, D. (1992). Structure and function of the nuclear pore complex. Annual Review of Cell
Biology, 8, 495-527. PDF

Hartl, P., Gottesfeld, J., and Forbes, D.J. (1993). Mitotic repression of transcription in vitro.
Journal Cell Biology, 120, 613-624. PDF

Gottesfeld, J.M., Wolf, V.J., Dang, T.L, Forbes, D.J. and Hartl, P. (1993). Mitotic repression of RNA
polymerase III transcription in vitro mediated by phosphorylation of a TFIIIB component.
Science, 263, 81-85. PDF

Hartl, P, Olson, E., Dang, T., and Forbes, D.J. (1994). Nuclear assembly with DNA in fractionated
Xenopus egg extracts: An unexpected role for glycogen in formation of a higher order chromatin intermediate.
Journal Cell Biology, 124, 235-248. PDF

Forbes, D.J. and Powers, M. (1994). Cytosolic factors in nuclear transport: what's importin?
Cell, 79, 931-934. PDF

Macaulay, C. and Forbes, D. (1995). Differential mitotic phosphorylation of proteins of the nuclear pore complex.
Journal. Biological Chemistry, 207, 254-262. PDF

Powers, M.A., Macaulay, C.G., Masiarz, F.R., and Forbes, D. (1995). Reconstituted nuclei depleted of a novel
vertebrate GLFG nuclear pore protein, p97, import but are defective in nuclear growth and replication.
Journal Cell Biology, 128, 721-736. PDF

Meier, E., Miller, B. and Forbes, D.J. (1995). Nuclear pore assembly studied with a biochemical assay for
annulate lamellae formation. Journal Cell Biology, 129 , 1459-1472. PDF

Ullman, K.S. and Forbes, D.J. (1995). RNA polymerase III transcription in synthetic nuclei assembled from
defined DNA templates. Molecular and Cellular Biology, 15 , 4873-4883. PDF

Macaulay, C. and Forbes, D.J. (1996). Assembly of the nuclear pore: biochemically distinct steps
revealed with NEM, GTPlS, and BAPTA. Journal of Cell Biology, 132, 5-20. PDF

Macaulay, C. and Forbes, D.J. (1996). Reconstitution of nuclear pore assembly and function.
Invited Review. Seminars in Cell and Developmental Biology, 7, 475-486. PDF

Powers, M.A., Forbes, D.J., Dahlberg, J.E., and Lund, E. (1997). The vertebrate GLFG nucleoporin, Nup98,
is an essential component of multiple RNA export pathways. Journal of Cell Biology, 136, 241-250. PDF

Gottesfeld, J. and Forbes, D. (1997). Mitotic repression of the transcriptional machinery. Invited Review.
Trends in Biochemical Sciences, 22, 197-202. PDF

Grandi, P., Dang, T, Pante, N., Shevchenko, A., Mann, M., Forbes, D. and Hurt, E. (1997). Nup93, a
vertebrate homolog of yeast Nic96, forms a complex with a novel 205 kd protein and is required for correct
nuclear pore assembly. Molecular Biology of the Cell, 8 , 2017-2038. PDF

Ullman, K.S., Powers, M, and Forbes, D.J. (1997). Invited Review. Nuclear export receptors: From
importin to exportin. Cell, 90, 967-970. PDF

Pasquinelli, A.E., Lund, E., Powers, M.A., Forbes, D.J., and Dalhberg, J. (1997). Inhibition of messenger RNA
export in vertebrate cells by nuclear export signal (NES) conjugates. P.N.A.S., 94, 14394-14399. PDF

Shah, S., Tugendreich, S., and Forbes, D. (1998). Major binding sites for the nuclear import receptor are the
internal nucleoporin Nup153 and the adjacent nuclear filament protein Tpr. Journal of Cell Biology, 8, 1376-1386. PDF

Shah, S., and Forbes, D. (1998). Separate nuclear import pathways converge on the nucleoporin Nup153
and can be dissected with dominant-negative inhibitors. Current Biology, 8, 1376-1386. PDF

Ullman, K.S., Shah, S., Powers, M.A., and Forbes, D.J. (1999). The nucleoporin Nup153 plays a critical role
in multiple types of nuclear export. Molecular Biology of the Cell , 10, 649-664. PDF

Miller, B., Powers, M.A., Park, C., Fischer, W., and Forbes, D.J. (2000). Identification of new vertebrate
nucleoporin, Nup188, with the use of a novel organelle trap assay. Molecular Biology of the Cell, 11, 3381-3396. PDF

Miller, B.R. and Forbes, D.J. (2000). Purification of the vertebrate nuclear pore by biochemical criteria.
Traffic, 1, 941-951. PDF

Vasu, S.K. and Forbes, D.J. (2001). Invited Review. Nuclear pores and nuclear assembly. Current Opinion
in Cell Biology, 13, 363-375. PDF

Vasu, S., Shah, S., Orjalo, A., Park, M., Fischer, W.H., and Forbes, D.J. (2001). Novel vertebrate nucleoporins
Nup 133 and Nup160 play a role in mRNA export. Journal of Cell Biology , 155, 339-353. PDF

Harel, A. and Forbes, D.J. (2001). News & Views: Welcome to the nucleus - CAN I take your coat?
Nature Cell Biology, 3, E267-E269. PDF

Harel, A. and Forbes, D.J. (2002). Nuclear transport: The bottom line. Cell, 109, 675-676. PDF

Harel, A., Orjalo, A., Vincent, T., Lachish-Zalait, A., Vasu, S., Shah, S., Zimmerman, E., Elbaum, M., and Forbes, D.J. (2003). Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores. Molecular Cell, 11, 853-864. PDF

Harel, A., Chan, R.C., Lachish-Zalait, A., Zimmerman, E., Elbaum, M., Forbes, D.J. (2003). Importin Beta Negatively Regulates Nuclear Membrane Fusion and NPC Assembly. Molecular Biology of the Cell, 14, 4387-4396. Full Text at MBC PDF

Harel, A., and Forbes, D.J. (2004). Invited review. Importin beta: Conducting a much larger cellular symphony. Molecular Cell, 16, 319-330. PDF

Chan, R.C. and Forbes, D.J. (2006). In vitro study of nuclear assembly and nuclear import using Xenopus egg extracts. Methods in Molecular Biology, vol. 322: Xenopus Protocols: Cell Biology and Signal Transduction. New Jersey: Humana Press. PDF

Lau, C.K., Delmar, V.A., and D. J. Forbes. (2006). Topology of yeast Ndc1p: Predictions for the human NDC1/NET3 homologues. The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology, 288A:681–694. PDF

Orjalo, A.V., Arnaoutov, A. , Shen, Z., Boyarchuk, Y., Zeitlin, S.G., Fontoura, B., Briggs, S., Dasso, M., and D.J. Forbes . (2006). The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly. Molecular Biology of the Cell 17, 3806-3818. Full Text at MBC PDF

Rasala, B.A., Orjalo, A.V., Shen, Z., Briggs, S., and D.J. Forbes. (2006). ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division. Proceedings of the National Academy of Science USA 103, 17801-17806. PDF

Resendes, K.K., Rasala, B.A., and D.J. Forbes. (2008). Centrin 2 localizes to the vertebrate nuclear pore and plays a role in mRNA and protein export. Molecular and Cellular Biology 28, 1755-1769. PDF

Brown, C.R., Kennedy, C.J., Delmar, V.A., Forbes, D.J., and P.A. Silver. (2008). Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. Genes and Development 22, 627-639. PDF

Delmar, V.A., Chan, R.C., and D.J. Forbes. (2008). Xenopus importin beta validates human importin beta as a cell cycle negative regulator. BMC Cell Biology 9, 14. PDF

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PROFESSIONAL AWARDS AND ACTIVITIES

1980-1983 American Cancer Society Junior & Senior Postdoct Fellowships
1985-1989 PEW Faculty Scholarship in the Biomedical Sciences
1990-1993 Editorial Board, Journal of Cell Biology
1992-1996 Editorial Board, Molcular Biology of the Cell
1994-1996 Vice-President of International Society of Cell Biologists (1 of 8)
1994-1997 Governing Council, American Society for Cell Biology
2000-2005, 2007-present Vice Chair, Section of Cell and Developmental Biology, UCSD
1994-present Editorial Board, Current Opinion in Cell Biology
2001-present Editorial Board, Traffic