Some Publications from the past few years
Tour, E., Hittinger, C.T. and McGinnis, W. (2005) Evolutionarily conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax. Development 132: 5271-5281. Tour_McGinnis.pdf
Pearson, J.C., Lemons, D., and McGinnis, W. (2005) Modulating Hox gene functions during animal body patterning. Nature Reviews Genetics 6: 893-904. Pearson-McGinnis.pdf
Mace, K.A., Pearson, J.C., and McGinnis, W. (2005) An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head. Science 308: 381-385. Epidermal barrier wound repair.pdf
Kosman, D., Mizutani, C.M., Lemons, D., Cox, W.G., McGinnis, W. and Bier, E. (2004) Multiplex detection of RNA expression in Drosophila Embryos. Science 305: 846. Multiplex detection of mRNA and miRNA.pdf
Hsia, C. and McGinnis, W. (2003) Evolution of transcription factor function. Current Opinion in Genetics and Development 13: 199-206 Transcription factor evolution and morphology.pdf
Bier, E. and McGinnis, W. (2003) Model organisms in development and disease. In Molecular Basis of Inborn Errors of Development. Eds. C.J. Epstein, R.P. Erikson, A. Wynshaw-Boris. pp. 25-45, Oxford University Press. Model organism review.pdf
Lohmann, I., McGinnis, N., Bodmer, M. and McGinnis, W. (2002) The Drosophila Hox protein Deformed sculpts head morphology by direct regulation of the apoptosis activator reaper. Cell 110: 457-466. Dfd/reaper.pdf
Ronshaugen, M., McGinnis, N., Chou, D., Zhao, J., Inglis, D. and McGinnis, W. (2002) Structure and expression patterns of Drosophila TULP and TUSP, members of the the tubby-like gene family. Mechanisms of Development 117: 209-215. DrosTulp.pdf
Ronshaugen, M., McGinnis, N. and McGinnis, W. (2002) Hox protein mutation and macroevolution of the insect body plan. Nature 415: 914-917. Hoxmacroevo.pdf
Veraksa, A, Del Campo, M. and McGinnis, W. (2000) Developmental patterning genes and their conserved functions: From model organism to humans. Molec. Gen. & Metabolism 69: 85-100. Online paper
Veraksa, A., McGinnis, N., Li, X., Mohler, J. and McGinnis, W. (2000) Cap 'n' Collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress Deformed homeotic function in the Drosophila head. Dev 127, 4023-4037. Online paper
Li, X., Veraksa, A. and McGinnis, W. (1999) A sequence motif distinct from Hox binding sites controls the specificity of a Hox response element. Dev 126, 5581.Online paper
Wiellette, E., Harding, K. W., Mace, K. A., Ronshaugen, M. R., Wang, F. Y. and McGinnis, W. (1999) spen encodes an RNP motif protein that interacts with Hox pathways to repress the development of head-like sclerites in the Drosophils trunk. Dev 126, 5373. Online paper
Del Campo, M., Jones, M. C., Veraksa, A. N., Curry, C. J., Jones, K. L., Mascarello, J. T., Ali-Kahn-Catts, Z., Drumheller, T. and McGinnis, W. (1999) Monodactylous limbs and abnormal genitalia are associated with hemizygosity for the human 2q31 region that includes the HOXD cluster. Am. J. Hum. Genet. 65, 104. Online paper
Li, X. and McGinnis, W. (1999) Activity regulation of Hox proteins, a mechanism for altering functional specificity in development and evolution. PNAS 96, 6802. Online paper
Li, X., Murre, C. and McGinnis, W. (1999) Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation. EMBO J 18, 198.Online paper
Wiellette, E. and McGinnis, W. (1999) Hox genes differentially regulate Serrate to generate segment-specific structures. Dev 126, 1985. Online paper