Supplemental Materials for:

Hagen, A.R., Barabote R.D., and Saier, M.H.Jr., 2004., "The Bestrophin Family of Anion Channels: Identification of Prokaryotic Homologues"




Figure S1: Multiple sequence alignment of all (75) eukaryotic bestrophin homologues. Two sequences, Ssc1 & Hsa5 (an incomplete sequence from pig and a splice variant from humans, respectively), were removed for the analyses presented in the paper.


Figure S2: Multiple sequence alignment of 66 animal bestrophin homologues.


Figure S3: Multiple sequence alignment of all (35) prokaryotic bestrophin homologues.


Figure S4: An expanded section of Figure 1, corresponding to positions 900-1600.


Figure S5: TMS prediction using the Tmap program for the eukaryotic bestrophin homologs.


Figure S6: TMS prediction using the Tmap program for the prokaryotic bestrophin homologs.



Table S1: TMS prediction using four methods for the eukaryotic bestrophin homologs.



Table S2: TMS prediction using four methods for the prokaryotic bestrophin homologs.