| Table SII | |||||||
| EbrA and EbrB restore multidrug resistance to E. coli cells expressing mutant ebrAB constructs | |||||||
| MICs (mg/ml) for BL21(DE3) expressing EbrA and EbrB, EbrBE14A and EbrA, EbrAE15A and EbrB, EbrAE15AB and EbrA, and EbrABE14A and EbrB*. | |||||||
| Drugs* | vectors | EbrB** | EbrBE14A | EbrAE15A | EbrAE15AB | EbrABE14A | |
| only | + | + | + | + | + | ||
| EbrA | EbrA | EbrB | EbrA | EbrB | |||
| ethidium bromide | 30 | >300 | 30 | 30 | >300 | >300 | |
| acriflavine | 10 | 110 | 10 | 10 | 110 | 90 | |
| pyronine Y | 8 | >100 | 8 | 8 | >100 | >100 | |
| TPA | 400 | 1,000 | 400 | 400 | 1,000 | 900 | |
| TPP | 400 | 1,000 | 400 | 400 | 1,000 | 1,000 | |
| * TPA - tetraphenylarsonium chloride, TPP - tetraphenylphosphonium chloride | |||||||
| ** Constructs on the upper position and the lower position were expressed from pET28a and pBAD28, respectively. | |||||||