Figure S2C. Subdomain D5 multiple alignment


Eco15 --GWWVNNGNHTN-IWLAANALCHAKNDGYNLPGITHLTS----GENKRTQGSLYGEWGN
Yfr2 --ENWFEGDSTSR-NWGNANADCNSRSE--VLPTIAQLTS----GEYIRQIGSLFGEWGD
Eco25 --SWWVNAGDAFM-IYSLAENFCS--SNGYTLPLGDHLNH----SRS-RGIGSLYSEWGD
Yps4 VNQWFINNNGVAL-NRADAATYCA--NAGYTTVSSSQVTNAIVWGMGTRAMGNLWSEWGD
Eco6 -KKWFTSLGATSSNTWDIINTSCSYGQMPSSLELAQRPSG----GVVPRKVGTLWGEYGN
Yps2 -PNRWIYDGGRSLVSSLEASRQCQGSDMSAVLESSRATNG------TRAPDGTLWGEWGS
: . * . . *.*:.*:*.

Eco15 VGAFSSNSQFTPGAYWTSESDDYSRHYYVQMLTGMTGSDAD-SSPQLTACR---
Yfr2 MMDYG----FPAANNWSSEQSGTSNYYYVVNSSRGRSSQAL-YTPGGTSVL---
Eco25 MGHYTTEAGFHSNMYWSSSPANSNEQYVVSLATGDQSVFEK-LGFAYATC----
Yps4 FNNYNVPGWEPAEFFWLSDNYNATDGLAASLSHGVLTTMGDPMAMIHVMCTRPI
Eco6 LKTYG--NAFSGTDYWTSTQLMGVHEKFNPETGISELGTGKSSGLCVEYY----
Yps2 LTAYS--SDWQSGEYWVKKTSTDFETMNMDTGALQPGPAYLAFPLCALSI----
. : * .