CLUSTAL X (1.81) multiple sequence alignment


Lpa2            -----MDVLKTIVNYVLNLGGPVFVPLIMFIIATIAGLKLKKSVLAALTLGVAFSGMTLV
Efae1           -----MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALTLGIAFSGMSMV
Lin3            -----MESLQSVIQFILNLGAAVFVPALMIIIGLIVRMKVRDAVSAGIILGVAFLGMNIV
Lmo3            -----MESLQSVIQFILNLGAAVFVPALMIIIGLIVRMKVRDAVSAGIILGVAFLGMNIV
Efa1            -MNTIIDLANTIFKPLIDLGAAPLMTIVLTLIALCFKVKPTRALEGGLKLGIALTGISAI
Lga3            -MNAIIDFANAIFKPLIDMGAPTIMLVVLTIIALCFRVKFSKALEGGMKLAIALTAIGDI
Cac1            -MNGIVEFANAVFKPLINLGAAPMMFIVLSVLAILMRVKVSKAIEGGLKLAIALTAIGQI
Spy1            MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTQALEGGIKLAIALTGIGAI
Sag2            -MQVFLNIVNKFFDPIIHMGSGVVMLIVMTGLAMIFGVKFSKALEGGIKLAIALTGIGAI
Spn1            -MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALEGGIKLAIALTGIGAI
Eco1            -------MFSEVMRYILDLGPTVMLPIVIIIFSKILGMKAGDCFKAGLHIGIGFVGIGLV
Sfl1            -------MFSEVMRYILDLGPTVMLPVVIIIFSKILGMKAGDCFKAGLHIGIGFVGIGLV
Sty1            -------MFSEIMRYILDLGPTVMLPLVIIVFSKLLGMKLGDCFKSGLHIGIGFVGIGLV
Sen1            -------MFSEIMRYILDLGPTVMLPLVIIVFSKLLGMKLGDCFKSGLHIGIGFVGIGLV
Kox1            -------MFSEIMRYILDLGPTVMLPIVIIIFSKILGMKLGDCFKSGLHIGIGFVGIGLV
Hso1            -------MFTEIMQYILDLGPAVMLPLVILILSLALGMKFGESFKAGLSIGIGFVGIGLV
Sty3            -----------MFDYILSLGGTVFVPIIMIIIGLIFRIPWLQAVKAGVTVGIGFVGMGLV
Sen5            -----------MFDYILSLGGTVFVPIIMIIIGLIFRIPWLQAVKAGVTVGIGFVGMGLV
Eco5            -----------MFDYILSLGGTVFVPIIMIVIGLIFRIPWLQAIKAGVTVGIGFVGMGLV
Oih1            -----MQGFVDFIQAFLGLGATVILPVAIFLIGLLFGQKPGKAFRSGLTIGVAFVGIFLV
Bha1            -----METAVSYIQGFLDLGATVILPVAIFLLGLAFGQKPGKAFRSGLTIGIAFVGIFLV
Sau1            -----MSYFTDFVRGFLDLGATVILPVVIFLLGLFFRQKIGAAFRSGLTIGVAFVGIFLV
Lmo1            -----MDTLLSGVQYVLNLGPTVILPIMIFFIALIFRVPAKKALRSAITIGIGFVGINLV
Lin1            -----MDTLLSGVQYVLNLGPTVILPIMIFFIALIFRVPAKKALRSAITIGIGFVGINLV
Lpa1            -----MKVLSDVVQSIINVGPSVMLPIIIFIVGLIFRVKPGKALTSGITVGIGMIGINLV
Eav1            -----MDGLMNVVQSILGAGASVMLPIIIFIVGIIFRVPIKKAIISGITVGIGMIGINLV
Tte1            ---------MSIIKYILDLGATVMLPIIIFLLALILGEKPGRAFRSALTIGIGFVGINLV
Sen3            -MNDIAHTLYTVVQYVLGFGPTVLLPLVLFFLALFFKVKPAKALRSSLIVGIGFVGIYAI
Sty2            -MNDIAHTLYTVVQYVLGFGPTVLLPLVLFFLALFFKVKPAKALRSSLIVGIGFVGIYAI
Eco3            -MNDIAHTLYNIVQYILGFGPTVMLPLVLFILALFFKVKPAKALRSSLTVGIGFVGIYAI
Ooe1            ---------MAILQWFVNTGASVMLPVLLFIFALVLGIKPGRAFKSGLTVGVGFVGLNLV
Lmo2            -----MDIILDFFKYIIGLGVTVMMPIIITILGVIFRKKISVAFKAGLTVGVGFVGLGVI
Lin2            -----MDIILDFFKYIIGLGVTVMMPIIITILGVIFRKKISVAFKAGLTVGVGFVGLGVI
Bth1            --------MEEVFKYIIGLGAAVMMPIIFTILGVCIGIKLPKALKSGLLVGVGFVGLSVV
Lga1            --------MNTINFFFNSFGTTIVIPTTIFIIALFVGYDPKKSLLYGLYAGIGLTGFSWI
Lga2            -------MLNNIHTFFNAFGATVIVPIMIFIIALFLKVKPKKAMMCGFYAGVGLTGFSWI
Sag1            -------MLEALHKFFEVFGAATVVPAMIFIVSLFLKVNPRRAFFSALRAGVGLTGFGWI
                                   *   .:   :  ..         ..  ..  .:.: .:  :

Lpa2            VNYMMDSISPAAKAMSKIFHLSLNAIDAGWTGVAAITWSYKSAFLFFPLLLAINFIMLTF
Efae1           IGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFFAVTIGVNFVLLLF
Lin3            IGFMIEALTPAAQGLAERTGINLSILDGGWTSMATLAWAWPFAFLMFPLQLGINAIMLVI
Lmo3            IGFMIEALTPAAQGLAERTGINLSILDGGWTSMATLAWAWPFAFLMFPLQLGINAIMLVI
Efa1            IGILTTAFSDAMASFVERTGISLNITDVGWAPLATITWGSPYTLYFLLIMVIVNVIMLIL
Lga3            MNLLTTSFAPAMNQFVKNTGMHKDIMDMGWAPLATITWGSPYTLYFLLVLIILNVLMLIF
Cac1            ISLLTTNFSGALQAFVKSTGINLSITDLGWAPVATITWGSMYTLFFLFILVIVNVIMLAL
Spy1            IGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPYTLYFLLVMLVVNIVMIVM
Sag2            IGILTGAFSESLQAFVKNTGINLSIIDVGWAPLATITWGSPYTLYFLLIMLIVNIVMIVM
Spn1            IGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWTLYFLLIMLIVNVVMLAM
Eco1            IGLMLDSIGPAAKAMAENFDLNLHVVDVGWPGSSPMTWASQIALVAIPIAILVNVAMLLT
Sfl1            IGLMLDSIGPAAKAMAENFDLNLHVVDVGWPGSSPMTWASQIALVAIPIAILVNVAMLLT
Sty1            IGLMLDSIGPAAKAMAEHFQINLHVIDVGWPGSSPMTWASQIALVAIPVAIGVNVLMLVT
Sen1            IGLMLDSIGPAAKAMAEHFQINLHVIDVGWPGSSPMTWASQIALVAIPVAIGVNVLMLVT
Kox1            IGLMLDSIGPAAKAMAEHFQLNLHVIDIGWPGSSPMTWASQIALVAIPIAIAVNIFMLVT
Hso1            IGLMLDSIGPAAKAMAHTFDIQLNVIDLGWPGASPMTWASQTALIAIPIAIAVNIAMLLL
Sty3            IVMAIDSLSPPIKVMIERFGLTLHVFDVGAGPASGVGYATAIGAMIIPVIFLLNVGMLVT
Sen5            IVMAIDSLSPPIKVMIERFGLTLHVFDVGAGPASGVGYATAIGAMIIPVIFLLNVGMLVT
Eco5            IVMAIDSLSPPIKVMIERFGLALHVFDVGAGPASGVGYATAIGAMIIPVIFLLNVAMLVT
Oih1            IDLLTLNLGPAAQGMVDRLGVNLNVIDIGWPATSSIAWASAIAAFIIPLGLAVNVVMLVT
Bha1            VDLLVLNLGPAAQGMVDRLGVDLNVIDVGWPATSSIAWASVVAAFIIPLGLIVNVIMLVT
Sau1            IDLLVKNLGPAAQAMVKNLGVSLNVIDVGWPATSSIAWASSVAAFIIPLGIIVNVVLLVT
Lmo1            ISLLSSNLGPAAQQMVERFGLNLTIIDAGWPAAAAASWASPVAAILIPICLVVNLALIFF
Lin1            ISLLSNNLGPAAQQMVERFGLNLTIIDAGWPAAAAASWASPVAAILIPICLVVNLALIFF
Lpa1            INLLTTSVGPAAQAMVKRFGFHLTIIDAGWPAVSAGTWAQPISAIMIPIILVVNVGLILL
Eav1            INVLTTNVGPAAQAMVERFGLNLTIIDAGWPAVSAGTWAQPIAAVMIPVILIVNLIMLAL
Tte1            IGLLVNNLGPAAQAMVEHMGVHLNVIDVGWPASAAIAFASKVGAFVIPIGLLVNIIMLAT
Sen3            FDILTSNVGPAAQAMVERTGISLPVVDLGWPPLAAITWGSPIAPFVIPLTMLINVAMLAL
Sty2            FDILTSNVGPAAQAMVERTGISLPVVDLGWPPLAAITWGSPIAPFVIPLTMLINVAMLAL
Eco3            FDILTSNVGPAAQAMVERTGINLPVVDLGWPPLSAITWGSPIAPFVIPLTILINVAMLAL
Ooe1            INLLTENLGPAAQAMVKNFGLNLHSIDIGWPAASAIAYGTVLGSIAIPVGIIVNVILLFV
Lmo2            TSLMLTTITPVTKALVENYNFKLTATDIGWGVGSSLAWGTEVVPFVFVAIIATNILMIAF
Lin2            TSLMLTTITPVTKALVENYNFKLTATDIGWGVGSSLAWGTEVVPFVFVAIIATNILMIAF
Bth1            TALLTSSLGPALSKMVEIYGLELGIFDMGWPSAAAVAYNTSVGAFIIPVCLGVNLLMLLT
Lga1            INQFTPIVIKIVYKMVNNTGIKRPIVDIGWEAGAVASFGSAIGLTFFIFGLLVEIILFAT
Lga2            INEFTPVVTKIVRQMVNNTGIKLPVVDIGWQAGSLASFGSPVGLTFFVFGLIAEFILFAV
Sag1            ISAFAPMVTKYIQQMVKTTGLHLPIVDIGWQAGSLTAFSSEIGLSFFVFGLLIELGLFLL
                       .      : .   .     * *    :   :        :   .  :  ::  

Lpa2            KWTKTLN-VDMWNVWNKIFTYVVVLYFTHN--------VFYGFIVAGIQIVLELKAGDMW
Efae1           NWTKTLN-VDMWNVWGKALTAYLVYYVSGS--------LAAGFLTAMVQVILELKLGDMF
Lin3            NKTKTLN-VDLWNVWGKILTAVLIIGVTQN--------VYLAFIVAGIQIVTELILCDAN
Lmo3            NKTKTLN-VDLWNVWGKILTAVLIIGVTQN--------VYLAFIVAGIQIVTELILCDAN
Efa1            NKTNTLD-VDIFDIWHLSIVGLFAIFCGAN--------LIIATILVIFIGVLKIINSDLM
Lga3            KRTNTLD-VDIFDVWHSAFVGLFAVFCGAP--------LWLATLLILLIGYLKIVNSDLM
Cac1            NKTNTLD-VDIFDVWHPAFCGILIMFYSKN--------LLVATIFVVFLGILKIINSDLM
Spy1            KKTDTLD-VDIFDIWHLSITGLLIMWYAARNHLPVFVSLLIATVAVILVGVLKIINSDLM
Sag2            KKTDTLD-VDIFDIWHLSITGLLIMWYAKKNNLPTLLSVIIATVAIIFVGVLKIINSDLM
Spn1            KKTDTLD-VDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIATAAIVLVGVLKIINSDLM
Eco1            RMTRVVN-VDIWNIWHMTFTGALLHLATGS--------WMIGMAGVVIHAAFVYKLGDWF
Sfl1            RMTRVVN-VDIWNIWHMTFTGALLHLATGS--------WMIGMAGVVIHAAFVYKLGDWF
Sty1            RMTRVVN-VDIWNIWHMTFTGAMLHLATGS--------YWLGILGVVVHAAFVYKLGDWF
Sen1            RMTRVVN-VDIWNIWHMTFTGAMLHLATGS--------YWLGILGVVVHAAFVYKLGDWF
Kox1            RMTRVVN-VDIWNIWHMTFTGAMLHIATGS--------YWIGILGVVIHAVFVYGLGDWF
Hso1            KMTRVVN-VDIWNIWHMTFTGALVHIATGS--------YWLGILGVIVHAAFVYKLGDWF
Sty3            RLTKTMN-VDIYNYWHYAITGTVVQLMTGS--------LIYGVLGAICHAALSLKMADWT
Sen5            RLTKTMN-VDIYNYWHYAITGTVVQLMTGS--------LIYGVLGAICHAALSLKMADWT
Eco5            RLTKTMN-VDIYNYWHYAITGTVVQLMTGS--------LIYGVLGAICHAALSLKMADWT
Oih1            KTTKTMN-VDIWNFWHYTFMGAVVYAVSDS--------IIQGLIAATIFQIVCLKIADWT
Bha1            KTTKTMN-VDIWNFWHYTFMAAVVYTVSDS--------IIQALIAAVMFQIVALKVADWT
Sau1            KVTKTMN-VDIWNFWHYTFTAAMVYAVSGS--------IWQALLAAVIFQVICLKVADWT
Lmo1            KVTKTLD-IDIWNYWHFIAAGATGYIVTGGN-------WWFAILCAIIYEVAVLWMADRT
Lin1            KVTKTLD-IDIWNYWHFIAAGATGYIVTGGN-------WWFAILCAIIYEVAVLWMADRT
Lpa1            NLTKTLD-IDIWNYWHMIAAAATAYVVTKN--------WWFAILCGIIYEIAVLIIADKT
Eav1            NRTKTLN-IDIWNYWHVSSVAATGYIVTKS--------FFFGILCGILFTIIIQIIADKT
Tte1            RLTKTVN-VDLWNYWHFAFTGALVTAATGS--------LTWGLVAAAINAAIVLLLADWT
Sen3            NKTRTVD-VDMWNYWHFALAGTLVYYSTGS--------FVLGLSAAAIAAIVVLKLADWS
Sty2            NKTRTVD-VDMWNYWHFALAGTLVYYSTGS--------FVLGLSAAAIAAIVVLKLADWS
Eco3            NKTRTVD-VDMWNYWHFALAGTLVYYSTGS--------LFFGLLAAAIAAVVVLKLADWS
Ooe1            GLTKILN-VDIWNYWHIAFTGSLVYVATND--------FALGILTMIVHSMLIYLMGDMV
Lmo2            KWTKTMD-VDIWNYWQPLFIASALYLTTGS--------MIIAVLSSIINMAIIFKIADWT
Lin2            KWTKTMD-VDIWNYWQPLFIASALYLTTGS--------MIIAILSSIINMAIIFKIADWT
Bth1            KTTRTVN-IDLWNYWHFAFIGAIVYFASDS--------IFWGFFAAIICYIITLVMADMT
Lga1            RITKVFMPSNLWNNFIFMLWGTLAFYITHD--------WWLSLGLSFFMLLYTLLFAEIQ
Lga2            GVTKVFMPSNLWNNFGFMIWGTLAFYVTHN--------WWISLGLSFFMLLYTLLLAEVQ
Sag1            GITRVFVPSNLWNNFGYMIWGTMAYAATGN--------FILSFAFMVFVLLYSLVMSEVL
                  *  .   :::: :                          .               :  

Lpa2            QRHIEDLTGMPG---VTVPHFVTLFAVILQPLNKLLDFIP--AMNRPFDSAALQKKIGVF
Efae1           QKHIQDLTGIPL---VTVTHFMTSAAVLLLPFNMIMDKIP--ALNKRADTNALKKKIGIF
Lin3            QRQIQELNGIPG---VTVSHGMMIFCIFLMPIDWLLKKIP--ALRKDMDANALKDKIGIF
Lmo3            QRQIQELNGIPG---VTVSHGMMIFCIFLMPLDWLLKKIP--ALRKDMDANALKDKIGIF
Efa1            KPTFNDLLNAPDTNPMTTTHMNYMMNPIIMVFDKIFDKLFPWLDKYDFDAAKLNSKIGFW
Lga3            KPTFDDLLDAPSSNPMTTTHMNYMMNPVIMVFNKFFDKCLPWLDKYDFDSAKLNEKIGFW
Cac1            KPTFNDLLNMPDTNPTTTTHLNYMMNPIVMVFDKLIDKFLPFLDKYDFDAAQLNNKIGFW
Spy1            KPTFDDLLGTGSQSPMTSTHMNYMMNPIIMVLDKIFDKVFPGLDKYDFDAAKLNKKIGFW
Sag2            KPTFDDLLGTGPTSPMTSTHMNYMMNPIIMVLDKLFDKVFPGLDKYDFDAAKLNKAIGFW
Spn1            KPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFFPGLDKYDFDAAKLNKKIGFW
Eco1            ARDTRNFFE-LEGIAIPHGTS-AYMGPIAVLVDAIIEKIP-GVNRIKFSADDIQRKFGPF
Sfl1            ARDTRNFFE-LEGIAIPHGTS-AYMGPIAVLVDAIIEKIP-GVNRIKFSADDIQRKFGPF
Sty1            AKDTRDYFG-LEGIAIPHGSS-AYLGPVAVLVDTIIEKIP-GLNRIHFSADDVQKRFGPF
Sen1            AKDTRDYFG-LEGIAIPHGSS-AYLSPVAVLVDTIIEKIP-GLNRIHFSADDVQKRFGPF
Kox1            AKDTCDFFG-LEGIAIPHGSS-AYLGPIAVLVDTIIEKIP-GLNRIHFRVDDIHRKFGPF
Hso1            SKDTKHFFE-LDGIAIPHGTS-AYLGPVAVLVDTIIEKIP-GLNKIHFSADDLQKRFGAL
Sty3            AKRVQNIVG-LEGISIPQGYG-SSSVPLFVLLDAIYEKIP-FMKGRNIDAQEIQKRYGMV
Sen5            TKRVQNIVG-LEGISIPQGYG-SSSVPLFVLLDAIYEKIP-FMKGRNIDAQEIQKRYGMV
Eco5            AKRVQNIVG-LEGISIPQGYG-SSSVPLFVLLDAIYEKIP-FMKGRNIDAQEIQKRYGMV
Oih1            QPMVEEFYD-MPGVSVATGST-ISYAPF-IFVVKGLQKIP-GLNKLNADPDSIQKRFGVF
Bha1            APMVSEFYE-LPGVSIATGST-ISYAPG-IWLVKGIQKIP-GIKHWNADPDTIQRRFGIF
Sau1            APMMSEFFD-LPGVSIATGST-ISYAPG-IYLVKLLQKVP-GLNKLDADPETIQKRFGAF
Lmo1            QPMVEEFYG-LKGISLPTGST-AAFGFIGIPVGWLIAKIP-GIKNIHVDPETIQKRFGIF
Lin1            QPMVEEFYG-LKGISLPTGST-AAFGFIGIPVGWLIAKIP-GIKNIHVDPETIQKRFGIF
Lpa1            APKVAEFYG-LDGISFPTGSA-AAYGLLGIPIGWVVSKIP-GIRKWDVDPQTIQKRFGVF
Eav1            APKVQEYYG-LEGISITTGSA-QGYAVLALPIGWLVDKIP-SINKLDVKPETIQKRFGIF
Tte1            AKMVQDFYG-LPGISLPHGFS-AAYVPIAIPLNKLIDKIP-VINKIEADTDTINKRFGIF
Sen3            APLVAKYFG-LEGISLPTLSS-VVFFPIGLLFDKIIDKIP-GVNRIHIDPENVQKKMGIF
Sty2            APLVAKYFG-LEGISLPTLSS-VVFFPIGLLFDKIIDKIP-GVNRIHIDPENVQKKMGIF
Eco3            APLVQKYFG-LEGISLPTLSS-VVFFPVGLLVDKIIDHIP-GLNRIHIDPETVQKKFGIF
Ooe1            APLVQKHYG-LPGITFTQGAS-LPGFALALPLNWIFDRIP-GISRFKLTPETIQKRMGVF
Lmo2            QKDVEDVLG-LEGISLPQIQT-TGWALVGYPMNWLLGKIP-GVRKINWSTEKVQSRLGIF
Lin2            QKDVEDVLG-LDGISLPQIQT-SGWALVGYPMNWLLGKIP-GVRKINWSTEKVQTRLGIF
Bth1            APAFQKFYDKMDGISIPQPFC-QSFVPFAIVINKLLDKIP-GFDKLNIDSEGMKKKFGLM
Lga1            ADRWATYYK--SKNITVCSAQNIVQTIPTILLDPLWNRLG--FNRTTLTPTTLKQKLGIF
Lga2            ADRWSSYYK--IENTTVCAAQNIVQTVPAILLDPLWDLLG--FNKANLTPAAFKDKFGVF
Sag1            ADRWSEYYG--VKNATINSIHNIETLIPALILDPLWNLLG--VNKVKLNPESLKTKLGIF
                                               .                    .:   *  

Lpa2            GDNTVMGAIIGVLLGFGAG--------------YSVSKSLNLAIQAATAMTLFPMISKLF
Efae1           SENSVMGFIIGLGLGFAAA--------------YGVSGSLNLAIQTATALSLFPMISKMF
Lin3            AENHVMGFIIGGLLGIAAG--------------YDVAKTLMLAMQAAAALTLFPMVAKLF
Lmo3            AENHVMGFIIGGLLGVAAG--------------YDVAKTLMLAMQAAAALTLFPMVAKLF
Efa1            GSKFAIGIYLGIFVGLLAG--------------QTPTQIFSLSFTAAVCLELFSLIGTWF
Lga3            GSRFAIGVYLGIFVSLLAGYNFTT--------EQGWKTMFTLSFTAGACIELFSVIGSWF
Cac1            GSKFAIGAYLGVFVGVLGH--------------QSIIKIFTLAFIGATCLELFSAIGSWF
Spy1            GSKFFIGMALGFVIGIMGDPHFTV---------ESIKNWFGLGFTAGACLELFSLIGSWF
Sag2            GSKFFIGMILGLVIGIMGNPVFSF---------AALGGWFSLGFTAGACLELFSLIGSWF
Spn1            GSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKGWLSLGLTAGVSLELFSLIGSWF
Eco1            GEPVTVGFVMGLIIGILAGYDVKGVLQ--------------LAVKTAAVMLLMPRVIKPI
Sfl1            GEPVTVGFVMGLIIGILAGYDVKGVLQ--------------LAVKTAAVMLLMPRMIKPI
Sty1            GEPVTVGFVMGLVIGVLAGYDAKAVLQ--------------LAVKTAAVMLLMPRVIKPI
Sen1            GEPVTVGFVMGLVIGVLAGYDTKAVLQ--------------LAVKTAAVMLLMPRVIKPI
Kox1            GEPVTVGFVMGLVIGSLAGYDLKGILQ--------------LAVKTAAVMLLMPRVIKPI
Hso1            GEPVTVGFIMGVVIGLLAGYSMKDVLQ--------------LAVKTATIMLLMPRVIKPI
Sty3            GDPVIIGVVLGLIFGLAAGEGFKGCAT--------------LMITVAAIMVLFPRMIRLI
Sen5            GDPVIIGVVLGLIFGLAAGEGFKGCAT--------------LMITVAAIMVLFPRMIRLI
Eco5            GDPVIIGVVLGLIFGLAAGEGFKGCAS--------------LMITVAAIMVLFPRMIRLI
Oih1            GDSMVIGLLLGAAIGALAGYGVGEIIN--------------IGISMAAVMVLMPRMVKIL
Bha1            GESIFIGLILGAAIGLLAGYNVGEVIE--------------IGMAMAAVMVLMPRMVKIL
Sau1            GESIFVGLILGLGIGVLAGYKPGDIIN--------------LGMSMAAVMVLMPRMVKIL
Lmo1            GEPMMMGLILGIAIGILAGYDVGAVAQ--------------LGMSMGAVMFLMPRMVKIL
Lin1            GEPMMMGLILGIAIGILAGYDVGAVAQ--------------LGMSMGAVMFLMPRMVKIL
Lpa1            GEPMVMGIVIGMLLAALGGYSVPNILK--------------LGMSMGGVMFLMPRMVKIL
Eav1            GEPMIMGIIIGMFLGLLGGYDFIGILQ--------------IGMNMGGVMFLMPRMVKIL
Tte1            GEPIVIGLILGVVLGILAKYDVKGILN--------------LGISMAAVMLLLPRMVRIL
Sen3            GEPMMVGTILGVLLGIIAGYDFKHILL--------------LGISIGGVMFILPRMVRIL
Sty2            GEPMMVGTILGVLLGIIAGYDFKHILL--------------LGISIGGVMFILPRMVRIL
Eco3            GEPMMVGTILGILLGVIAGYDFKKVLL--------------LGISIGGVMFILPRMVRIL
Ooe1            GDSTVIGLVIGLVIGFLAKYSLAKTLQ--------------LGINTAAVLVVMPRMVSLL
Lmo2            GEPMLMGLIIGGGLAAIAQMPLSQVLQ--------------TGVTIAASLVLIPRMVSLL
Lin2            GEPMLMGLIIGGGLAAIAQMPLSQVLQ--------------TGVTIAASLVLIPRMVSLL
Bth1            GEPLFLGIVIGCGIGALGCASWKEVLDG-------IPGILGLGIKMGAVMELIPRITSLF
Lga1            GEPPILGAALGLFISLIANIKALNQVS-------AWEQIFQFTIQLSAVITIFPLIATVF
Lga2            GEPTTLGAILGIVIGILGNIKDLTTIK-------AWGQILQFAVQLSAVMTIFPLVTNVF
Sag1            GEPMTLGFILGVIIGVLGSLRNLASID-------TWGGILGFAVALAAVMTIFPLITGVF
                ..   :*  :*  ..  .                         .  .  : ::. :   :

Lpa2            MQALSPIADAMSDFMKKHFN-----------GRE-VFIGLDWPILAGRNELWVTVVILVP
Efae1           MQSLSPLADAMSEFMKKRFK-----------DRE-VYIGLDWPILAGRSEIWVTAILLVP
Lin3            MQALSPLSDGISEFMKRKFK-----------NRE-LFIGLDWPILAGCSEVWVAIVLMVP
Lmo3            MQALSPLSDGISEFMKRKFK-----------NRE-LFIGLDWPILAGCSEVWVAIVLMVP
Efa1            IAAVEPLSQGITDFASNKLK-----------GRT-LNIGLDWPFLAGRAEIWAAANVLAP
Lga3            IASVEPLSQGISNFATSKFK-----------GRT-FNVGLDWPFIAGRAEIWAAANVLAP
Cac1            IAAVEPLSQGITNFLSKRLK-----------GRT-FNIGIDWPFIAGRAEMWAVANILAP
Spy1            IAAVEPLSQGITNFANARMH-----------GRR-FNIGLDWPFIAGRAEIWACANILAP
Sag2            IAAVEPLSQGITNFANGKMH-----------GRR-FNIGLDWPFIAGRAEIWACANILAP
Spn1            IAAVEPLSQGITNVATKRLQ-----------GRK-FNIGLDWPFIAGRAEIWACANVLAP
Eco1            MDGLTPIAKQARSRLQAKFG-----------GQE-FLIGLDPALLLGHTAVVSASLIFIP
Sfl1            MDGLTPIAKQARSRLQAKFG-----------GQE-FLIGLDPALLLGHTAVVSASLIFIP
Sty1            MDGLTPIAKHARKRLQAKFG-----------GQE-FLIGLDPALLLGHTSVVSASLIFIP
Sen1            MDGLTPIAKHARKRLQAKFG-----------GQE-FLIGLDPALLLGHTSVVSASLIFIP
Kox1            MDGLNPIAKQARSRLQAKFG-----------GQD-FLIGLDPALLLGHTSVVSASLIFIP
Hso1            MDGLAPIAKQARKKLQARFG-----------GSD-FLIGLDPALLLGHTSVVSASLIFIP
Sty3            VEGLMPISDGARKFFQKHFK-----------GRE-VFIGLDTAVTLGHPTTIAVGLLLIP
Sen5            VEGLMPISDGARKFFQKHFK-----------GRE-VFIGLDTAVTLGHPTTIAVGLLLIP
Eco5            VEGLLPISDGARKFFQKYFK-----------GRE-VYIGLDTAVTLGHPTTIAVGLLLIP
Oih1            MEGLMPVSESAREWLNKHFG-----------DRE-INIGLDAAVLLGHPSVIATALILTP
Bha1            MEGLMPVSESAREWLNKRFG-----------DRE-IHIGLDAAVLLGHPSVISTALILVP
Sau1            MEGLMPVSESARTWLNKRFG-----------ERE-IYIGLDAAVALGHPAVISTALILVP
Lmo1            MEGLIPISESAREFMKSRFK-----------GRE-LYIGLDAALSIGHPANISTGLILVP
Lin1            MEGLIPISESARDFMKSRFK-----------GRE-LYIGLDAALSIGHPANISTGLILVP
Lpa1            MEGLIPIQEGAQKLLQEKYG-----------NRK-IYLGMDAALSTGSPATLATGLLMVP
Eav1            MEGLIPIQEGAQKLLQSRYG-----------DRE-IYLGMDAALATGSPAALSTGLLMVP
Tte1            MEGLIPISEAAKAFMQKRFQ-----------GRE-FYIGLDSAIAVGHPAAIATALVLVP
Sen3            MEGLLPLSEAIKKYLNAKYP-----------GRDDLFIGLDIAVAVGNPAIISTALILTP
Sty2            MEGLLPLSEAIKKYLNAKYP-----------GRDDLFIGLDIAVAVGNPAIISTALILTP
Eco3            MEGLLPLSEAIKKYLNAKYP-----------DRDDLYIGLDIAVAVGNPAIISTALLLTP
Ooe1            MEGLTPISEGANEFVKKRFP-----------GRQ-LFIGMDSALAVGQEAVLSASLILVP
Lmo2            MDGLTVISEAAHEFMEKRFP-----------GRE-LFIGLDSAVGIGHPFVLSLGLLMIP
Lin2            MDGLTVISEAAHEFMEKRFP-----------GRE-LFIGLDSAVGIGHPFVLSLGLLMIP
Bth1            IEGLKPISDATRELIAKKYK-----------SNTGLSIGMSPALVIGHPTTLVVSLLLIP
Lga1            NMAFTPLAEQIDKSRKQKQKSNTVIEINPIHDKKRWFLAVDDSVGYGESATIISGIILIP
Lga2            SKAFTPLAKQIDKERKQSK--NQDSEIDPIHDKKRWFLAVDDGVGYGESATIISGIILIP
Sag1            ASAFAPLAEAVERNKKKES-----QAEQGALDKKRWFIAVDDGVGFGEPATIIAGLILVP
                  ..  : .                            :.:.  .  *         :: *

Lpa2            VMLVFAMLLP--GNTVLPFAGIINLSFVVAALLLTG-ANLLRMLVLGIITTPIFLYGATY
Efae1           VFIGYAIILP--GNQVLPLAGIINYSIAVGGLLLTG-GNLARMLILGIITMPIYLYGATY
Lin3            VTLIFALILP--GNGVLPFAGILNISLCAPALIVTG-GNLIRMIILGTITTPIFLYVSTF
Lmo3            VTLIFALILP--GNGVLPFAGILNISLCAPALIVTG-GNLIRMIILGTITTPIFLYVSTF
Efa1            IMLLEAIVLP--GNKLLPLGGIIAMGVTPALLVVTR-GKLIRMIIIGAIELPLFLWSGTL
Lga3            IMMVEAMVIP--GNRLMPLGGIIAMGVTPALLVVTR-GKIIRMIIIGTIELPIFLWAGTL
Cac1            ILLIFSLILP--GNKLLPLGGIIAMGITPALLVVTR-GKMIRMIIIGILEIPIFLWAGTV
Spy1            IMLIEAVLLSKVGNGILPLAGIIAMGMTPALLVVTR-GRLIRMIIFGSLLLPLFLLSGTM
Sag2            IMLVEAILLSKVGNGILPLAGIIAMGVTPALLVVTR-GRLIRMITFGTLLLPLFLLSGTM
Spn1            IMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTR-GKLLRMIIFGTLLLPLFLLSGTL
Eco1            LTILIAVCVP--GNQVLPFGDLATIGFFVAMAVAVHRGNLFRTLISGVIIMSITLWIATQ
Sfl1            LTILIAVCVP--GNQVLPFGDLATIGFFVAMAVAVHRGNLFRTLISGVIIMSITLWIATQ
Sty1            LTILIAVLVP--GNQVLPFGDLATIGFFIAMAVAVHQGNLFRTLISGVIIMGITLWIATQ
Sen1            LTILIAVLVP--GNQVLPFGDLATIGFFIAMAVAVHQGNLFRTLISGVIIMGITLWIATQ
Kox1            LSILIAVLVP--GNQVLPFGDLATIGFFVAMAVAVHQGNLFRTLISGIILMGITLWIATQ
Hso1            LTILIAVFLP--GNQVLPFGDLATIGFFVAMAVAVHQGNLFRTLISGLIIMSMTLWIATQ
Sty3            IMLILASILP--GNKVLPLADLPVAPFFICMATVIHRGDLIRTLLSGIIVMITVLLIATQ
Sen5            IMLILASILP--GNKVLPLADLPVAPFFICMATVIHRGDLIRTLLSGIIVMITVLLIATQ
Eco5            IMLILASILP--GNKVLPLADLPVAPFFICMATVIHRGDLVRTLISGVIVMITVLLIATQ
Oih1            VTVLLAVILP--GNAVLPFGDLATIPFVIAFVVGAARGNIIHSVIVGTIMIAVSLYVATD
Bha1            LTVLLAVILP--GNALLPFGDLATIPFIVAFIVGAARGNIIHSVLAGAIMIALSLYMATD
Sau1            ITVLLAVILP--GNQVLPFGDLATIPFVVAFIVGAARGNIIHSVIVGTIMIAISLYIATD
Lmo1            ITLFLAVIIP--GNKVLPFGDLATIPFYVSFVVASRKGNILHSVLAGTVVIALALLMATD
Lin1            ITLFLAVIIP--GNKVLPFGDLATIPFYVSFVVASRKGNILHSVLAGTVVIALALLMATD
Lpa1            ITLFLAIILP--GNRVLPFGDLATIPFFAALIVPSRKGNIVHSVLSATIVMVFALLMATD
Eav1            ITLFLAVILP--GNRVLPFGDLATIPFFAALVVPSRKGNILHSVISLTVVMAVALLMATN
Tte1            ITILLAIILP--GNHVLPFGDLATIPFMVVMVVPVTKGNVFRSILIGTIVIGVGLWIATN
Sen3            ISVFIAFLLP--GNKVLPLGDLANLAVMASMIVLACRGNIFRAVITAIPVIIADLWIATK
Sty2            ISVFIAFLLP--GNKVLPLGDLANLAVMASMIVLACRGNIFRAVITAIPVIVADLWIATK
Eco3            ISVFIAFVLP--GNEVLPLGDLANLAVMASMIALASRGNIFRTVLAAIPVIIADLWIATK
Ooe1            VTIFLSVILP--GNSVLPFGDLATIPFMIAIMAAVFRGDIFRTIIGGIVDITISLYIASW
Lmo2            ITLILAFILP--GNKVLPLADLTALPFYMIFAIVPSKGNLFRGIFTGIVIVIITLYLSGA
Lin2            ITLILAFILP--GNKVLPLADLTALPFYMIFAIVPSKGNLFRGIFTGIVIVIITLYLSGA
Bth1            VTIFLAVILP--GNRFLPLASLAGMFYLFPMILPITKGNVVKSFIIGLVALIVGLYFVTE
Lga1            IMLILAFLLP--GNKTLPIVDLVLLPFMVESIVAITNGNILKIIATSIVWFSLGLYTASW
Lga2            IMVVIAFLLP--GNKTLPVVDLISLPFMVESIVAITDGNILKVIANGIVWFSLGLYAASW
Sag1            IMVVISLILP--GNEALPVVDLIAIPFMIEAMIAVSKGNILKAILNGIIWFSLGLYAASA
                : :  :  :.  **  :*. .:               . : : .          *     

Lpa2            FAPIITNLAKSTGTVK--VQAGQQLSWSTFEGPD-FRLFFAKAFTGEWWAIGISILWLLG
Efae1           LAPILSDLAEKSGAVEG-IKKGQLITWSSIEGPE-FRVLFAEAFNRNILAIVGCVIFLGL
Lin3            FAGTITDLAHSTGAIS--LKAGQQITWSTLEYPV-FRYIFAEASQFTILGFIFVAIWVLL
Lmo3            FAGTITDLAHSTGAIS--LKAGQQITWSTLEYPV-FRYIFAEASQFTILGFIFVAIWVVL
Efa1            IAPFVTETAKKVGAFPAGLNNNTLISHTTMEGPM-EKFLGYLVGNASQG-QLEFILYACL
Lga3            VAPFVTQVAHQVGAN---IPAHTLVSDTTMEGPI-EKFLGYLVGNAWKH-QGMFIVYAIL
Cac1            IAPCVTNLAKQVGAFPKGLSTSTLISHSTCEGPI-EKFLSVLIGKFFQGGNITTGLYVIL
Spy1            IAPFATELAKKVGAFPAGASAGSLITHSTLEGPM-EKIFGYVIGQATTG-QIASIITLII
Sag2            IAPFATELAKKVGAFPAGARAGSLITHSTLEGPM-EKIFGYVIGKATTG-QLSAIITLII
Spn1            IAPFATELAKGVGAFPEGVSQTQLITHSTLEGPI-EKLLGWTIGNTTTG-DIKAILGAVA
Eco1            TIGLHTQLAANAGALKAGGMV---ASMDQGG-----SPITWLLIQVFSPQNIPGFIIIGA
Sfl1            TIGLHTQPAANAGALKAGGMV---ASMDQGG-----SPITWLLIQVFSPQNIPGFIIIGA
Sty1            TIGLHTQLAANAGALKAGGQV---ASLDQGG-----SPITWLLIQLFTWQNIVGFAVIAI
Sen1            TIGLHTQLAANAGALKAGAQV---ASLDQGG-----SPITWLLIQLFTWQNIVGFAVIAI
Kox1            TIGLHTQLAANAGALKAGGLV---ASMDQGG-----SPDYLATHSSSSPGKRGGFAVSCH
Hso1            TIAYHTQLAANAGTLKAGEQV---ASMDQGG-----SPITYLMIQVLTFENIVGMTIIAI
Sty3            FAPYFTDMALKGGFSFAAENA---QITALSV-----GNMFGWSISELMSLGMIGVVIVVG
Sen5            FAPYFTDMALKGGFSFAAENA---QITALSV-----GNMFGWSISELMSLGMIGVVIVVG
Eco5            FAPYFTEMALKGGFSFAGESA---QISALSV-----GNMFGWSISELMSLGIIGVVVAVG
Oih1            IAPLFTDMATNAEINLPEGSA-MVSSIDQGG-----NIVNWVIWRFFDLFN---------
Bha1            IAPVFTKMAENSNFNMPEGSA-LISSIDQGG-----NLVNWIIWKLFALFN---------
Sau1            VAPIFTDMAKGTNVQMPKGSS-EISSIDQGG-----NIVNYLIFKLFSLFN---------
Lmo1            FGLVHTEMMKG-VYEFPKGAT-QVSTLDMGG-----NFFNWVILKFSQAWAAIF------
Lin1            FGLVHTEMMKG-VYEFPKGAT-QVSTLDMGG-----NFFNWAILKFSQAWAAIF------
Lpa1            FGPTLTSMMHG-IVAFPKGAS-EVTNLDTGG-----NILNWLILKLSQLVQPLFN-----
Eav1            FAPVITEMAQG-IVKFPEGAA-EITNLDTGG-----NFLKWIFLKFSELVATVM------
Tte1            VAPLFTQVAAEAAFKFPTGAT-EISSICDGA-----NPLTWVILQIMRLF----------
Sen3            IAPFITGMAKDVNFKMAEGSSGQVSSFLDGG-----NPFRFWLLEIFNGNIIAIGLIPVL
Sty2            IAPFITGMAKDVNFKMAEGSSGQVSSFLDGG-----NPFRFWLLEIFNGNIIAIGLIPVL
Eco3            IAPFITGMAKDVNFKFAEGSSGQVSSFLDGG-----NPFRFWLLEIFNGNIIAIGLVPVI
Ooe1            VAPMLTQAAKLAKFNMHGNSS--ISVLSDGG-----SWTTLLIVGLGKTMTWTGISLIGI
Lmo2            AAPLMTELAGQIGYNIPKDAVEVTSLAVG---------TQWYTWIVYYGLHWFGGIL---
Lin2            AAPLMTELAGQIGYNIPKDAVEVTSLAVG---------TQWYTWIVYYGLHWFGGIL---
Bth1            LAGFFTMAAKDVYAATGDPTVNIPAGFEGGALDFASSLFCWGIFHLTYSLKIIGPAILVA
Lga1            LGPIYTNAIAHYGVSIPAGIILVTSFSLMAQPFNALIFVAFISRSPFWISLCIIIYLILL
Lga2            LGSIYTGAISQYGATIPAGIVLVTSFNLMARPLNALVFAAFISQNPLWISLCIIVYLALL
Sag1            LGPIYTEAVKHFGTALPAGVTLIMSFNLLAHPLTALVFFAWISGNPLYIGVTVVIYLAFL
                     :                                                      

Lpa2            FIWLYIDQNKIKLPSQRYVLAGSAQSSSTTAAPSETTTTSAGSLDDLDDMDFSNTSKSSA
Efae1           FVLLYKYMIKAKVPSERYAELQK-------------------------------------
Lin3            LVFYVKMMKKRTIELEKASS----------------------------------------
Lmo3            LVFYVKMMKKRTIELEKASS----------------------------------------
Efa1            ALVAYLLIFIWYAKQMKKRNIIYAQKAQ--------------------------------
Lga3            AIAAYILIFWWYSREMKKRNAKYAAAAKEA------------------------------
Cac1            ALAAYLALFVWYAKQMKKRNTEYAKVKTED------------------------------
Spy1            FVAIYLGLFAWYANQMKARNAEYAKTMT--------------------------------
Sag2            FATAYLGLFMWYAKQMKRRNAEYAANQK--------------------------------
Spn1            FLVFYIGIFAWYRKQMIKRNEEYAAKAK--------------------------------
Eco1            IYLTGIFMTWRRARGFIKQEKVVLAE----------------------------------
Sfl1            IYLTGIFMTWRRARGFTKQEKAVLAE----------------------------------
Sty1            IYLAGVLLTWRRARQFVAAEKATALQQSQIAS----------------------------
Sen1            IYLAGVLLTWRRARQFVAAEKATALQQSQIAS----------------------------
Kox1            RG----------------------------------------------------------
Hso1            IYFCGVFLTWRRAKSYEKEIVAQSAQN---------------------------------
Sty3            IVASIILVLRKRELPE--------------------------------------------
Sen5            IVASIILVLRKRELPE--------------------------------------------
Eco5            IVASVVLFLRKRELSE--------------------------------------------
Oih1            ------------------------------------------------------------
Bha1            ------------------------------------------------------------
Sau1            ------------------------------------------------------------
Lmo1            ------------------------------------------------------------
Lin1            ------------------------------------------------------------
Lpa1            ------------------------------------------------------------
Eav1            ------------------------------------------------------------
Tte1            ------------------------------------------------------------
Sen3            ALVIYGVFRLTKGTVYA-------------------------------------------
Sty2            ALIIYGVFRLTKGTVYA-------------------------------------------
Eco3            ALVLYGIFRMTRSTVYA-------------------------------------------
Ooe1            AVLAIMIWQNKFRKPKIEKNV---------------------------------------
Lmo2            ------------------------------------------------------------
Lin2            ------------------------------------------------------------
Bth1            LALGMAVYNRIRMKRNDAKNAAND------------------------------------
Lga1            FILRRYRSQIWIYLNKMAAKNIQIRHKSSFQK----------------------------
Lga2            FILRKYRPQIWTYLNKMATKNVHANQDLKPSPKD--------------------------
Sag1            FLLRTHRESIYAYLKTMADKNSGYEGSCEKIFIAED------------------------
                                                                            

Lpa2            SNNATKVSLNDLDGLNFSNTSKHNNSR
Efae1           ---------------------------
Lin3            ---------------------------
Lmo3            ---------------------------
Efa1            ---------------------------
Lga3            ---------------------------
Cac1            ---------------------------
Spy1            ---------------------------
Sag2            ---------------------------
Spn1            ---------------------------
Eco1            ---------------------------
Sfl1            ---------------------------
Sty1            ---------------------------
Sen1            ---------------------------
Kox1            ---------------------------
Hso1            ---------------------------
Sty3            ---------------------------
Sen5            ---------------------------
Eco5            ---------------------------
Oih1            ---------------------------
Bha1            ---------------------------
Sau1            ---------------------------
Lmo1            ---------------------------
Lin1            ---------------------------
Lpa1            ---------------------------
Eav1            ---------------------------
Tte1            ---------------------------
Sen3            ---------------------------
Sty2            ---------------------------
Eco3            ---------------------------
Ooe1            ---------------------------
Lmo2            ---------------------------
Lin2            ---------------------------
Bth1            ---------------------------
Lga1            ---------------------------
Lga2            ---------------------------
Sag1            ---------------------------